Self-demixing of mRNA copies buffers mRNA:mRNA and mRNA:regulator stoichiometries
Andrés H. Cardona, Szilvia Ecsedi, Mokrane Khier, Zhou Yi, Alia Bahri, Amira Ouertani, Florian Valero, Margaux Labrosse, Sami Rouquet, Stéphane Robert, Agnes Loubat, Danielle Adekunle, Arnaud Hubstenberger
NR2F1 shapes mitochondria in the mouse brain, providing new insights into Bosch-Boonstra-Schaaf optic atrophy syndrome
Sara Bonzano, Eleonora Dallorto, Ivan Molineris, Filippo Michelon, Isabella Crisci, Giovanna Gambarotta, Francesco Neri, Salvatore Oliviero, Ruth Beckervordersandforth, Dieter Chichung Lie, Paolo Peretto, Serena Bovetti, Michèle Studer, Silvia De Marchis
Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities
Torsten Felske, Chiara Tocco, Sophie Péron, Kawssar Harb, Christian Alfano, Chiara Galante, Benedikt Berninger, Michèle Studer
Coalescent RNA-localizing and transcriptional activities of SAM68 modulate adhesion and subendothelial basement membrane assembly
Zeinab Rekad, Michaël Ruff, Agata Radwanska, Dominique Grall, Delphine Ciais, Ellen Van Obberghen-Schilling
Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer
Valentina Cigliola, Adam Shoffner, Nutishia Lee, Jianhong Ou, Trevor J Gonzalez, Jiaul Hoque, Clayton J Becker, Yanchao Han, Grace Shen, Timothy D Faw, Muhammad M Abd-El-Barr, Shyni Varghese, Aravind Asokan, Kenneth D Poss
RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa
Aline Chessel, Noémie De Crozé, Maria Dolores Molina, Laura Taberner, Philippe Dru, Luc Martin, Thierry Lepage
A network embedding approach to identify active modules in biological interaction networks
Claude Pasquier, Vincent Guerlais, Denis Pallez, Raphaël Rapetti-Mauss, Olivier Soriani
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A Youssef, Alain de Bruin, Elvira R M Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Y chromosome toxicity does not contribute to sex-specific differences in longevity
Rénald Delanoue, Charlène Clot, Chloé Leray, Thomas Pihl, Bruno Hudry
RNA granules in neuronal plasticity and disease
Karl E Bauer, Bruna R de Queiroz, Michael A Kiebler, Florence Besse
Higher-order epistasis shapes natural variation in germ stem cell niche activity
Sarah R Fausett, Asma Sandjak, Bénédicte Billard, Christian Braendle
Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
Ferdinand Marlétaz, Arnaud Couloux, Julie Poulain, Karine Labadie, Corinne Da Silva, Sophie Mangenot, Benjamin Noel, Albert J Poustka, Philippe Dru, Cinta Pegueroles, Marco Borra, Elijah K Lowe, Guy Lhomond, Lydia Besnardeau, Stéphanie Le Gras, Tao Ye, Daria Gavriouchkina, Roberta Russo, Caterina Costa, Francesca Zito, Letizia Anello, Aldo Nicosia, Maria Antonietta Ragusa, Marta Pascual, M Dolores Molina, Aline Chessel, Marta Di Carlo, Xavier Turon, Richard R Copley, Jean-Yves Exposito, Pedro Martinez, Vincenzo Cavalieri, Smadar Ben Tabou de Leon, Jenifer Croce, Paola Oliveri, Valeria Matranga, Maria Di Bernardo, Julia Morales, Patrick Cormier, Anne-Marie Geneviève, Jean Marc Aury, Valérie Barbe, Patrick Wincker, Maria Ina Arnone, Christian Gache, Thierry Lepage
Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors
Yasmine Neirijnck, Pauline Sararols, Françoise Kühne, Chloé Mayère, Lahiru Chamara Weerasinghe Arachchige, Violaine Regard, Serge Nef, Andreas Schedl
A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Arnaud Landra-Willm, Ameya Karapurkar, Alexia Duveau, Anne Amandine Chassot, Lucille Esnault, Gerard Callejo, Marion Bied, Stephanie Häfner, Florian Lesage, Brigitte Wdziekonski, Anne Baron, Pascal Fossat, Laurent Marsollier, Xavier Gasull, Eric Boué-Grabot, Michael A. Kienzler, Guillaume Sandoz
Asymmetric activity of NetrinB controls laterality of the Drosophila brain
François Lapraz, Céline Boutres, Cloé Fixary-Schuster, Bruna R. De Queiroz, Pierre-Yves Plaçais, Delphine Cerezo, Florence Besse, Thomas Préat, Stéphane Noselli
Regulation of the collagen IV network by the basement membrane protein perlecan is crucial for squamous epithelial cell morphogenesis and organ architecture
Raphaël Bonche, Prune Smolen, Aline Chessel, Séverine Boisivon, Sabrina Pisano, Aaron Voigt, Sébastien Schaub, Pascal Thérond, Sandrine Pizette
Biological effects of the loss of homochirality in a multicellular organism
Agnes Banreti, Shayon Bhattacharya, Frank Wien, Koichi Matsuo, Matthieu Réfrégiers, Cornelia Meinert, Uwe Meierhenrich, Bruno Hudry, Damien Thompson, Stéphane Noselli
An RNA-immunoprecipitation protocol to identify RNAs associated with RNA-binding proteins in cytoplasmic and nuclear Drosophila head fractions
Marjorie Heim, Lauren Blot, Florence Besse
SK2 channels set a signalling hub bolstering CAF-triggered tumourigenic processes in pancreatic cancer
Raphael Rapetti-Mauss, Jérémy Nigri, Camille Berenguier, Pascal Finetti, Sarah Simha Tubiana, Bonnie Labrum, Benoit Allegrini, Bernard Pellissier, Georgios Efthymiou, Zainab Hussain, Corinne Bousquet, Nelson Dusetti, François Bertucci, Hélène Guizouarn, Patricia Melnyk, Franck Borgese, Richard Tomasini, Olivier Soriani
The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression
Zeinab Rekad, Valerio Izzi, Rijuta Lamba, Delphine Ciais, Ellen Van Obberghen-Schilling
Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation
Julien Fierling , Alphy John , Barthélémy Delorme , Alexandre Torzynski , Guy B Blanchard , Claire M Lye , Anna Popkova , Grégoire Malandain , Bénédicte Sanson , Jocelyn Étienne , Philippe Marmottant , Catherine Quilliet , Matteo Rauzi
RNP components condense into repressive RNP granules in the aging brain
Kavya Vinayan Pushpalatha, Mathilde Solyga, Akira Nakamura, Florence Besse
High-Resolution Live Imaging of Axonal RNP Granules in Drosophila Pupal Brain Explants
Caroline Medioni , Jeshlee Vijayakumar , Anne Ephrussi , Florence Besse
Detecting Stress Granules in Drosophila Neurons
Fabienne De Graeve, Nadia Formicola, Kavya Vinayan Pushpalatha, Akira Nakamura, Eric Debreuve, Xavier Descombes, Florence Besse
Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection
Rocio Garcia-Rodas, Hayet Labbaoui, François Orange, Norma Solis, Oscar Zaragoza, Scott G Filler, Martine Bassilana, Robert A Arkowitz
The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
Vishnu Muraleedharan Saraswathy, Akshai Janardhana Kurup, Priyanka Sharma, Sophie Polès, Morgane Poulain, Maximilian Fürthauer
Live-Imaging of Axonal Cargoes in Drosophila Brain Explants Using Confocal Microscopy
Caroline Medioni, Anne Ephrussi, Florence Besse
Regulation of two-pore-domain potassium TREK channels and their involvement in pain perception and migraine
Pablo Ávalos Prado , Anne-Amandine Chassot , Arnaud Landra-Willm , Guillaume Sandoz
Photopharmacological approaches for dissecting potassium channel physiolog
Stephanie Häfner, Guillaume Sandoz
Germ cell apoptosis is critical to maintain Caenorhabditis elegans offspring viability in stressful environments
Sarah Fausett, Nausicaa Poullet, Clotilde Gimond, Anne Vielle, Michele Bellone, Christian Braendle
Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development
Julien Marcetteau, Tamàs Matusek, Frédéric Luton, Pascal P Thérond
A Myosin Light Chain Is Critical for Fungal Growth Robustness in Candida albicans
Charles Puerner, Antonio Serrano, Rohan S Wakade, Martine Bassilana, Robert A Arkowitz
Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection
Manish Grover, Michael K Fasseas, Clara Essmann, Kenneth Liu, Christian Braendle, Marie-Anne Félix, Sally L Glockling, Michalis Barkoulas
Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction
Fabio Da Silva, Fariba Jian Motamedi, Lahiru Chamara Weerasinghe Arachchige, Amelie Tison, Stephen T Bradford, Jonathan Lefebvre, Pascal Dolle, Norbert B Ghyselinck, Kay D Wagner, Andreas Schedl
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex
Fabio Da Silva, Kaiqing Zhang, Anneline Pinson, Edoardo Fatti, Michaela Wilsch-Bräuninger, Jessica Herbst, Valerie Vidal, Andreas Schedl, Wieland B Huttner, Christof Niehrs
KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism
Anthony A Ruberto, Aline Gréchez-Cassiau, Sophie Guérin, Luc Martin, Johana S Revel, Mohamed Mehiri, Malayannan Subramaniam, Franck Delaunay, Michèle Teboul
TREK channel activation suppresses migraine pain phenotype
Pablo Ávalos Prado, Arnaud Landra-Willm, Clément Verkest, Aurore Ribera, Anne-Amandine Chassot, Anne Baron, Guillaume Sandoz
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries
Morgane Le Rolle, Filippo Massa, Pam Siggers, Laurent Turchi, Agnès Loubat, Bon-Kyoung Koo, Hans Clevers, Andy Greenfield, Andreas Schedl, Marie-Christine Chaboissier, Anne-Amandine Chassot
The FibromiR miR-214-3p Is Upregulated in Duchenne Muscular Dystrophy and Promotes Differentiation of Human Fibro-Adipogenic Muscle Progenitors
Nicole Arrighi, Claudine Moratal, Grégoire Savary, Julien Fassy, Nicolas Nottet, Nicolas Pons, Noémie Clément, Sandy Fellah, Romain Larrue, Virginie Magnone, Kevin Lebrigand, Nicolas Pottier, Claude Dechesne, Georges Vassaux, Christian Dani, Pascal Peraldi, Bernard Mari
Model learning to identify systemic regulators of the peripheral circadian clock
Julien Martinelli, Sandrine Dulong, Xiao-Mei Li, Michèle Teboul, Sylvain Soliman, Francis Lévi, François Fages, Annabelle Ballesta
Composite morphogenesis during embryo development
Alphy John, Matteo Rauzi
Adrenal cortex renewal in health and disease
Rodanthi Lyraki, Andreas Schedl
Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth
Sandrine Pizette, Tamás Matusek, Bram Herpers, Pascal P Thérond, Catherine Rabouille
A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation
Adrien Rougny, Loïc Paulevé, Michèle Teboul, Franck Delaunay
Phosphorylated Gβ is a directional cue during yeast gradient tracking
Rashida Abdul-Ganiyu, Leon A Venegas, Xin Wang, Charles Puerner, Robert A Arkowitz, Brian K Kay, David E Stone
The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease
Rodanthi Lyraki, Andreas Schedl
Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain
Nadia Formicola, Marjorie Heim, Jérémy Dufourt, Anne-Sophie Lancelot, Akira Nakamura, Mounia Lagha, Florence Besse
A two-tier junctional mechanism drives simultaneous tissue folding and extension
Alphy John, Matteo Rauzi
High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture
Roxane Elaldi, Patrice Hemon, Luciana Petti, Estelle Cosson, Belinda Desrues, Anne Sudaka, Gilles Poissonnet, Ellen Van Obberghen-Schilling, Jacques-Olivier Pers, Veronique M Braud, Fabienne Anjuère, Aïda Meghraoui-Kheddar
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans
Daehan Lee, Stefan Zdraljevic, Lewis Stevens, Ye Wang, Robyn E Tanny, Timothy A Crombie, Daniel E Cook, Amy K Webster, Rojin Chirakar, L Ryan Baugh, Mark G Sterken, Christian Braendle, Marie-Anne Félix, Matthew V Rockman, Erik C Andersen
The role of the tumor matrix environment in progression of head and neck cancer
Angélique Saint, Ellen Van Obberghen-Schilling
A fine-tuned azobenzene for enhanced photopharmacology in vivo
Vanessa A Gutzeit, Amanda Acosta-Ruiz, Hermany Munguba, Stephanie Häfner, Arnaud Landra-Willm, Bettina Mathes, Jürgen Mony, Dzianis Yarotski, Karl Börjesson, Conor Liston, Guillaume Sandoz, Joshua Levitz, Johannes Broichhagen
Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination
Chloé Mayère, Yasmine Neirijnck, Pauline Sararols, Chris M Rands, Isabelle Stévant, Françoise Kühne, Anne-Amandine Chassot, Marie-Christine Chaboissier, Emmanouil T Dermitzakis, Serge Nef
The GTPase Rab8 differentially controls the long- and short-range activity of the Hedgehog morphogen gradient by regulating Hedgehog apico-basal distribution
Tanvi Gore, Tamás Matusek, Gisela D'Angelo, Cécile Giordano, Thomas Tognacci, Laurence Lavenant-Staccini, Catherine Rabouille, Pascal P Thérond
Cellular and Supracellular Planar Polarity: A Multiscale Cue to Elongate the Drosophila Egg Chamber
Anna Popkova, Matteo Rauzi, Xiaobo Wang
A dynamic and mosaic basement membrane controls cell intercalation in Drosophila ovaries
Véronique Van De Bor, Vincent Loreau, Marilyne Malbouyres, Delphine Cerezo, Audrey Placenti, Florence Ruggiero, Stéphane Noselli
A single-nucleotide change underlies the genetic assimilation of a plastic trait
Paul Vigne, Clotilde Gimond, Céline Ferrari, Anne Vielle, Johan Hallin, Ania Pino-Querido, Sonia El Mouridi, Laure Mignerot, Christian Frøkjær-Jensen, Thomas Boulin, Henrique Teotónio, Christian Braendle
Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks
Georgios Efthymiou, Agata Radwanska, Anca-Ioana Grapa, Stéphanie Beghelli-de la Forest Divonne, Dominique Grall, Sébastien Schaub, Maurice Hattab, Sabrina Pisano, Mallorie Poet, Didier F Pisani, Laurent Counillon, Xavier Descombes, Laure Blanc-Féraud, Ellen Van Obberghen-Schilling
Developmental mechanisms of adrenal cortex formation and their links with adult progenitor populations
Ioannis Oikonomakos, Lahiru Chamara Weerasinghe Arachchige, Andreas Schedl
Selfing is the safest sex for Caenorhabditis tropicalis
Luke M Noble, John Yuen, Lewis Stevens, Nicolas Moya, Riaad Persaud, Marc Moscatelli, Jacqueline L Jackson, Gaotian Zhang, Rojin Chitrakar, L Ryan Baugh, Christian Braendle, Erik C Andersen, Hannah S Seidel, Matthew V Rockman
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
John P Russell, Xinhong Lim, Alice Santambrogio, Val Yianni, Yasmine Kemkem, Bruce Wang, Matthew Fish, Scott Haston, Anaëlle Grabek, Shirleen Hallang, Emily J Lodge, Amanda L Patist, Andreas Schedl, Patrice Mollard, Roel Nusse, Cynthia L Andoniadou
Ubiquitous Selfish Toxin-Antidote Elements in Caenorhabditis Species
Eyal Ben-David, Pinelopi Pliota, Sonya A Widen, Alevtina Koreshova, Tzitziki Lemus-Vergara, Philipp Verpukhovskiy, Sridhar Mandali, Christian Braendle, Alejandro Burga, Leonid Kruglyak
Circulating Hedgehog: a fresh view of a classic morphogen
Elodie Prince, Julien Marcetteau, Pascal P Thérond
KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies
Pablo Ávalos Prado, Stephanie Häfner, Yannick Comoglio, Brigitte Wdziekonski, Christophe Duranton, Bernard Attali, Jacques Barhanin, Guillaume Sandoz
Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo
Swann Floc'hlay, Maria Dolores Molina, Céline Hernandez, Emmanuel Haillot, Morgane Thomas-Chollier, Thierry Lepage, Denis Thieffry
Two different sources of Perlecan cooperate for its function in the basement membrane of the Drosophila wing imaginal disc
Raphaël Bonche, Aline Chessel, Séverine Boisivon, Prune Smolen, Pascal Thérond, Sandrine Pizette
Local retinoic acid signaling directs emergence of the extraocular muscle functional unit
Glenda Evangelina Comai, Markéta Tesařová, Valérie Dupé, Muriel Rhinn, Pedro Vallecillo-García, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, François Spitz, Sigmar Stricker, Tomáš Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh
The Rosmarinus Bioactive Compound Carnosic Acid Is a Novel PPAR Antagonist That Inhibits the Browning of White Adipocytes
Cécilia Colson, Pierre-Louis Batrow, Nadine Gautier, Nathalie Rochet, Gérard Ailhaud, Franck Peiretti, Ez-Zoubir Amri
Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Martin Werdermann, Ilona Berger, Laura D Scriba, Alice Santambrogio, Pia Schlinkert, Heike Brendel, Henning Morawietz, Andreas Schedl, Mirko Peitzsch, Aileen J F King, Cynthia L Andoniadou, Stefan R Bornstein, Charlotte Steenblock
WT1 activates transcription of the splice factor kinase SRPK1 gene in PC3 and K562 cancer cells in the absence of corepressor BASP1
Tareg Belali, Chigeru Wodi, Bethany Clark, Man-Kim Cheung, Tim J Craig, Gabrielle Wheway, Nicole Wagner, Kay-Dietrich Wagner, Stefan Roberts, Sean Porazinski, Michael Ladomery
Functions of Wnt and Hedgehog-containing extracellular vesicles in development and disease
Tamás Matusek, Julien Marcetteau, Pascal P Thérond
Mechanical force-induced morphology changes in a human fungal pathogen
Charles Puerner, Nino Kukhaleishvili, Darren Thomson, Sebastien Schaub, Xavier Noblin, Agnese Seminara, Martine Bassilana, Robert A Arkowitz
Cell intercalation in a simple epithelium
Matteo Rauzi
A Natural Mutational Event Uncovers a Life History Trade-Off via Hormonal Pleiotropy
Bénédicte Billard, Paul Vigne, Christian Braendle
Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes
Martin Paré, Cédric Y Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux
The Emerging Role of PPAR Beta/Delta in Tumor Angiogenesis
Siyue Du, Nicole Wagner, Kay-Dietrich Wagner
PPARs and Angiogenesis-Implications in Pathology
Nicole Wagner, Kay-Dietrich Wagner
MCD diet-induced steatohepatitis generates a diurnal rhythm of associated biomarkers and worsens liver injury in Klf10 deficient mice
Pierre S Leclère, Déborah Rousseau, Stéphanie Patouraux, Sophie Guérin, Stéphanie Bonnafous, Aline Gréchez-Cassiau, Anthony A Ruberto, Carmelo Luci, Malayannan Subramaniam, Albert Tran, Franck Delaunay, Philippe Gual, Michèle Teboul
Tenascin-C orchestrates an immune suppressive tumor microenvironment in oral squamous cell carcinoma
Caroline Spenlé, Thomas Loustau, Devadarssen Murdamoothoo, William Erne, Stéphanie Beghelli-de la Forest Divonne, Romain Veber, Luciana Petti, Pierre Bourdely, Matthias Mörgelin, Eva Maria Brauchle, Gérard Crémel, Vony Randrianarisoa, Abdouramane Camara, Samah Rekima, Sebastian Schaub, Kelly Nouhen, Thomas Imhof, Uwe Hansen, Nicodème Paul, Raphael Carapito, Nicolas Pythoud, Aurelie Hirschler, Christine Carapito, Hélène Dumortier, Christopher G Mueller, Manuel Koch, Katja Schenke-Layland, Shigeyuki Kon, Anne Sudaka, Fabienne Anjuere, Ellen Van Obberghen-Schilling, Gertraud Orend
High prevalence for obesity in severe COVID-19: Possible links and perspectives towards patient stratification
Isabelle Dugail, Ez-Zoubir Amri, Nicolas Vitale
Defined p16 High Senescent Cell Types Are Indispensable for Mouse Healthspan
Laurent Grosse, Nicole Wagner, Alexander Emelyanov, Clement Molina, Sandra Lacas-Gervais, Kay-Dietrich Wagner, Dmitry V Bulavin
COUP-TFI/Nr2f1 Orchestrates Intrinsic Neuronal Activity during Development of the Somatosensory Cortex
Isabel Del Pino, Chiara Tocco, Elia Magrinelli, Andrea Marcantoni, Celeste Ferraguto, Giulia Tomagra, Michele Bertacchi, Christian Alfano, Xavier Leinekugel, Andreas Frick, Michèle Studer
NR2F1 Regulates Regional Progenitor Dynamics in the Mouse Neocortex and Cortical Gyrification in BBSOAS Patients
Michele Bertacchi, Anna Lisa Romano, Agnès Loubat, Frederic Tran Mau-Them, Marjolaine Willems, Laurence Faivre, Philippe Khau van Kien, Laurence Perrin, Françoise Devillard, Arthur Sorlin, Paul Kuentz, Christophe Philippe, Aurore Garde, Francesco Neri, Rossella Di Giaimo, Salvatore Oliviero, Silvia Cappello, Ludovico D'Incerti, Carolina Frassoni, Michèle Studer
Oxytocin Controls Chondrogenesis and Correlates With Osteoarthritis
Christian H Roux, Didier F Pisani, Pierre Gillet, Eric Fontas, Hédi Ben Yahia, Mansour Djedaini, Damien Ambrosetti, Jean-François Michiels, Patricia Panaia-Ferrari, Véronique Breuil, Astrid Pinzano, Ez-Zoubir Amri
Sox8 and Sox9 Act Redundantly for Ovarian-To-Testicular Fate Reprogramming in the Absence of R-spondin1 in Mouse Sex Reversals
Nainoa Richardson, Isabelle Gillot, Elodie P Gregoire, Sameh A Youssef, Dirk de Rooij, Alain de Bruin, Marie-Cécile De Cian, Marie-Christine Chaboissier
Retinoic Acid Synthesis by ALDH1A Proteins Is Dispensable for Meiosis Initiation in the Mouse Fetal Ovary
Anne-Amandine Chassot, Morgane Le Rolle, Geneviève Jolivet, Isabelle Stevant, Jean-Marie Guigonis, Fabio Da Silva, Serge Nef, Eric Pailhoux, Andreas Schedl, Norbert B Ghyselinck, Marie-Christine Chaboissier
Context-dependent regulation of endothelial cell metabolism: differential effects of the PPARβ/δ agonist GW0742 and VEGF-A
Ashton Faulkner, Eleanor Lynam, Robert Purcell, Coleen Jones, Colleen Lopez, Mary Board, Kay-Dietrich Wagner, Nicole Wagner, Carolyn Carr, Caroline Wheeler-Jones
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and the neuroendocrine stress axis.
Steenblock C, Todorov V, Kanczkowski W, Eisenhofer G, Schedl A, Wong ML, Licinio J, Bauer M, Young AH, Gainetdinov RR, Bornstein SR
Single-cell RNA-seq with spike-in cells enables accurate quantification of cell-specific drug effects in pancreatic islets
Brenda Marquina-Sanchez, Nikolaus Fortelny, Matthias Farlik, Andhira Vieira, Patrick Collombat, Christoph Bock, Stefan Kubicek
PPAR Beta/Delta and the Hallmarks of Cancer
Nicole Wagner, Kay-Dietrich Wagner
ERK-mediated Loss of miR-199a-3p and Induction of EGR1 Act as a "Toggle Switch" of GBM Cell Dedifferentiation Into NANOG- And OCT4-positive Cells
Fabien Almairac, Laurent Turchi, Nathalie Sakakini, David N Debruyne, Sarah Elkeurti, Elisabet Gjernes, Beatrice Polo, Laurence Bianchini, Denys Fontaine, Philippe Paquis, Herve Chneiweiss, Marie-Pierre Junier, Patrick Verrando, Fanny Burel-Vandenbos, Thierry Virolle
R-spondin signalling is essential for the maintenance and differentiation of mouse nephron progenitors
Vidal VP, Jian-Motamedi F, Rekima S, Gregoire EP, Szenker-Ravi E, Leushacke M, Reversade B, Chaboissier MC, Schedl A
Shaping Up the Tumor Microenvironment With Cellular Fibronectin
Georgios Efthymiou, Angélique Saint, Michaël Ruff, Zeinab Rekad, Delphine Ciais, Ellen Van Obberghen-Schilling
Mouse Gonad Development in the Absence of the Pro-Ovary Factor WNT4 and the Pro-Testis Factor SOX9
Furong Tang, Nainoa Richardson, Audrey Albina, Marie-Christine Chaboissier, Aitana Perea-Gomez
R-spondin2 signaling is required for oocyte-driven intercellular communication and follicular growth
De Cian MC, Gregoire EP, Le Rolle M, Lachambre S, Mondin M, Bell S, Guigon CJ, Chassot AA, Chaboissier MC
The Drosophila Actin Nucleator DAAM Is Essential for Left-Right Asymmetry
Anil Chougule, François Lapraz, István Földi, Delphine Cerezo, József Mihály, Stéphane Noselli
A Cdc42-mediated Supracellular Network Drives Polarized Forces and Drosophila Egg Chamber Extension
Anna Popkova, Orrin J Stone, Lin Chen, Xiang Qin, Chang Liu, Jiaying Liu, Karine Belguise, Denise J Montell, Klaus M Hahn, Matteo Rauzi, Xiaobo Wang
Downregulation of thioredoxin-1-dependent CD95 S-nitrosation by Sorafenib reduces liver cancer
Raúl González, María A Rodríguez-Hernández, María Negrete, Kalina Ranguelova, Aurelie Rossin, Carmen Choya-Foces, Patricia de la Cruz-Ojeda, Antonio Miranda-Vizuete, Antonio Martínez-Ruiz, Sergio Rius-Pérez, Juan Sastre, José A Bárcena, Anne-Odile Hueber, C Alicia Padilla, Jordi Muntané
Hedgehog Signaling Modulates Glial Proteostasis and Lifespan
Andrew Rallis, Juan A. Navarro, Mathias Rass, Amelie Hu, Serge Birman, Stephan Schneuwly and Pascal P. Therond
Growth and Maturation in Development: A Fly's Perspective
Renald Delanoue, Nuria M Romero