The Wilms’ Tumor Suppressor WT1 in Cardiomyocytes: Implications for Cardiac Homeostasis and Repair
Sandra Díaz del Moral, Nicole Wagner and Kay-Dietrich Wagner
A Dual Role of the Senescence Marker P16Ink4a in Liver Endothelial Cell Function
Kay-Dietrich Wagner, Hasan Safwan-Zaiter and Nicole Wagner
FGF8-mediated gene regulation affects regional identity in human cerebral organoids
Michele Bertacchi, Gwendoline Maharaux, Agnès Loubat, Matthieu Jung, Michèle Studer
An image-based RNAi screen identifies the EGF.R signaling pathway as a regulator of Imp/ IGF2BP RNP granules
Fabienne De Graeve, Eric Debreuve, Kavya Vinayan Pushpalata, Xuchun Zhang, Somia Rahmoun, Djampa Kozlowski, Nicholas Cedilnik, Jeshlee Vijayakumar, Paul Cassini, Sebastien Schaub, Xavier Descombes, Florence Besse
Regulating translation in aging: from global to gene-specific mechanisms
Mathilde Solyga, Amitabha Majumdar, Florence Besse
Life history in Caenorhabditis elegans: from molecular genetics to evolutionary ecology
Christian Braendle, Annalise Paaby
Brain bilateral asymmetry - insights from nematodes, zebrafish, and Drosophila
François Lapraz, Cloé Fixary-Schuster, Stéphane Noselli
Whole-brain annotation and multi-connectome cell typing of Drosophila
FlyWire Consortium/Stéphane Noselli
Neuronal wiring diagram of an adult brain
FlyWire Consortium/Stéphane Noselli
Sex determination, it is all about timing
Élodie Grégoire, Marie-Cécile De Cian, Mélanie Detti, Isabelle Gillot, Aitana Perea-Gomez, Marie-Christine Chaboissier
In vitro differentiation of mouse pluripotent stem cells into corticosteroid-producing adrenocortical cells
Ioannis Oikonomakos, Melina Tedesco, Fariba Jian Motamedi, Mirko Peitzsch, Serge Nef, Stefan R Bornstein, Andreas Schedl, Charlotte Steenblock, Yasmine Neirijnck
Cellular sex throughout the organism underlies somatic sexual differentiation
Chloé Hérault, Thomas Pihl, Bruno Hudry
Myosin1G promotes Nodal signaling to control zebrafish left-right asymmetry
Akshai Janardhana Kurup, Florian Bailet, Maximilian Fürthauer
Maternal TGF-β ligand Panda breaks the radial symmetry of the sea urchin embryo by antagonizing the Nodal type II receptor ACVRII
Praveen Kumar Viswanathan, Aline Chessel, Maria Dolores Molina, Emmanuel Haillot, Thierry Lepage
The evolutionarily conserved choroid plexus contributes to the homeostasis of brain ventricles in zebrafish
Inyoung Jeong, Søren N Andreassen, Linh Hoang, Morgane Poulain, Yongbo Seo, Hae-Chul Park, Maximilian Fürthauer, Nanna MacAulay, Nathalie Jurisch-Yaksi
Natural variation in the Caenorhabditis elegans egg-laying circuit modulates an intergenerational fitness trade-off
Laure Mignerot, Clotilde Gimond, Lucie Bolelli, Charlotte Bouleau, Asma Sandjak, Thomas Boulin, Christian Braendle
Disrupted protein interaction dynamics in a genetic neurodevelopmental disorder revealed by structural bioinformatics and genetic code expansion
Valerio Marino, Wanchana Phromkrasae, Michele Bertacchi, Paul Cassini, Krittalak Chakrabandhu, Daniele Dell'Orco, Michèle Studer
Asymmetric Adrenals: Sexual Dimorphism of Adrenal Tumors
Nicole Bechmann, Mats Leif Moskopp, Georgiana Constantinescu, Anthony Stell, Angela Ernst, Frank Berthold, Frank Westermann, Jingjing Jiang, Longfei Lui, Elisabeth Nowak, Stephanie Zopp, Karel Pacak, Mirko Peitzsch, Andreas Schedl, Martin Reincke, Felix Beuschlein, Stefan R Bornstein, Martin Fassnacht, Graeme Eisenhofer
A mechanical wave travels along a genetic guide to drive the formation of an epithelial furrow during Drosophila gastrulation
Anna Popkova, Urška Andrenšek, Sophie Pagnotta, Primož Ziherl, Matej Krajnc, Matteo Rauzi
Central role of the habenulo-interpeduncular system in the neurodevelopmental basis of susceptibility and resilience to anxiety in mice
Malalaniaina Rakotobe, Niels Fjerdingstad, Nuria Ruiz-Reig, Thomas Lamonerie, Fabien D'Autréaux
Hijacking of internal calcium dynamics by intracellularly residing viral rhodopsins
Ana-Sofia Eria-Oliveira, Mathilde Folacci, Anne Amandine Chassot, Sandrine Fedou, Nadine Thézé, Dmitrii Zabelskii, Alexey Alekseev, Ernst Bamberg, Valentin Gordeliy, Guillaume Sandoz, Michel Vivaudou
A live-cell ergosterol reporter for visualization of the effects of fluconazole on the human fungal pathogen Candida albicans
Antonio Serrano, Miguel A Basante-Bedoya, Martine Bassilana, Robert A Arkowitz
A spatial statistical framework for the parametric study of fiber networks: application to fibronectin deposition by normal and activated fibroblasts
Anca-Ioana Grapa, Georgios Efthymiou, Ellen Van Obberghen-Schilling, Laure Blanc-Féraud and Xavier Descombes
The −KTS splice variant of WT1 is essential for ovarian determination in mice
Elodie P. Gregoire, Marie-Cécile De Cian, Roberta Migale, Aitana Perea-Gomez, Sébastien Schaub, Natividad Bellido-Carreras, Isabelle Stévant, Chloé Mayère, Yasmine Neirijnck, Agnès Loubat, Paul Rivaud, Miriam Llorian Sopena, Simon Lachambre, Margot M. Linssen, Peter Hohenstein, Robin Lovell-Badge, Serge Nef, Frédéric Chalmel, Andreas Schedl, Marie-Christine Chaboissier
Metabolic regulation of proteome stability via N-terminal acetylation controls male germline stem cell differentiation and reproduction
Charlotte M François, Thomas Pihl, Marion Dunoyer de Segonzac, Chloé Hérault, Bruno Hudry
Self-demixing of mRNA copies buffers mRNA:mRNA and mRNA:regulator stoichiometries
Andrés H. Cardona, Szilvia Ecsedi, Mokrane Khier, Zhou Yi, Alia Bahri, Amira Ouertani, Florian Valero, Margaux Labrosse, Sami Rouquet, Stéphane Robert, Agnes Loubat, Danielle Adekunle, Arnaud Hubstenberger
NR2F1 shapes mitochondria in the mouse brain, providing new insights into Bosch-Boonstra-Schaaf optic atrophy syndrome
Sara Bonzano, Eleonora Dallorto, Ivan Molineris, Filippo Michelon, Isabella Crisci, Giovanna Gambarotta, Francesco Neri, Salvatore Oliviero, Ruth Beckervordersandforth, Dieter Chichung Lie, Paolo Peretto, Serena Bovetti, Michèle Studer, Silvia De Marchis
Lmo4 synergizes with Fezf2 to promote direct in vivo reprogramming of upper layer cortical neurons and cortical glia towards deep-layer neuron identities
Torsten Felske, Chiara Tocco, Sophie Péron, Kawssar Harb, Christian Alfano, Chiara Galante, Benedikt Berninger, Michèle Studer
Coalescent RNA-localizing and transcriptional activities of SAM68 modulate adhesion and subendothelial basement membrane assembly
Zeinab Rekad, Michaël Ruff, Agata Radwanska, Dominique Grall, Delphine Ciais, Ellen Van Obberghen-Schilling
Spinal cord repair is modulated by the neurogenic factor Hb-egf under direction of a regeneration-associated enhancer
Valentina Cigliola, Adam Shoffner, Nutishia Lee, Jianhong Ou, Trevor J Gonzalez, Jiaul Hoque, Clayton J Becker, Yanchao Han, Grace Shen, Timothy D Faw, Muhammad M Abd-El-Barr, Shyni Varghese, Aravind Asokan, Kenneth D Poss
RAS-independent ERK activation by constitutively active KSR3 in non-chordate metazoa
Aline Chessel, Noémie De Crozé, Maria Dolores Molina, Laura Taberner, Philippe Dru, Luc Martin, Thierry Lepage
A network embedding approach to identify active modules in biological interaction networks
Claude Pasquier, Vincent Guerlais, Denis Pallez, Raphaël Rapetti-Mauss, Olivier Soriani
Crosstalk between androgen receptor and WNT/β-catenin signaling causes sex-specific adrenocortical hyperplasia in mice
Rodanthi Lyraki, Anaëlle Grabek, Amélie Tison, Lahiru Chamara Weerasinghe Arachchige, Mirko Peitzsch, Nicole Bechmann, Sameh A Youssef, Alain de Bruin, Elvira R M Bakker, Frank Claessens, Marie-Christine Chaboissier, Andreas Schedl
Y chromosome toxicity does not contribute to sex-specific differences in longevity
Rénald Delanoue, Charlène Clot, Chloé Leray, Thomas Pihl, Bruno Hudry
RNA granules in neuronal plasticity and disease
Karl E Bauer, Bruna R de Queiroz, Michael A Kiebler, Florence Besse
Higher-order epistasis shapes natural variation in germ stem cell niche activity
Sarah R Fausett, Asma Sandjak, Bénédicte Billard, Christian Braendle
Analysis of the P. lividus sea urchin genome highlights contrasting trends of genomic and regulatory evolution in deuterostomes
Ferdinand Marlétaz, Arnaud Couloux, Julie Poulain, Karine Labadie, Corinne Da Silva, Sophie Mangenot, Benjamin Noel, Albert J Poustka, Philippe Dru, Cinta Pegueroles, Marco Borra, Elijah K Lowe, Guy Lhomond, Lydia Besnardeau, Stéphanie Le Gras, Tao Ye, Daria Gavriouchkina, Roberta Russo, Caterina Costa, Francesca Zito, Letizia Anello, Aldo Nicosia, Maria Antonietta Ragusa, Marta Pascual, M Dolores Molina, Aline Chessel, Marta Di Carlo, Xavier Turon, Richard R Copley, Jean-Yves Exposito, Pedro Martinez, Vincenzo Cavalieri, Smadar Ben Tabou de Leon, Jenifer Croce, Paola Oliveri, Valeria Matranga, Maria Di Bernardo, Julia Morales, Patrick Cormier, Anne-Marie Geneviève, Jean Marc Aury, Valérie Barbe, Patrick Wincker, Maria Ina Arnone, Christian Gache, Thierry Lepage
Single-cell transcriptomic profiling redefines the origin and specification of early adrenogonadal progenitors
Yasmine Neirijnck, Pauline Sararols, Françoise Kühne, Chloé Mayère, Lahiru Chamara Weerasinghe Arachchige, Violaine Regard, Serge Nef, Andreas Schedl
A photoswitchable inhibitor of TREK channels controls pain in wild-type intact freely moving animals
Arnaud Landra-Willm, Ameya Karapurkar, Alexia Duveau, Anne Amandine Chassot, Lucille Esnault, Gerard Callejo, Marion Bied, Stephanie Häfner, Florian Lesage, Brigitte Wdziekonski, Anne Baron, Pascal Fossat, Laurent Marsollier, Xavier Gasull, Eric Boué-Grabot, Michael A. Kienzler, Guillaume Sandoz
Asymmetric activity of NetrinB controls laterality of the Drosophila brain
François Lapraz, Céline Boutres, Cloé Fixary-Schuster, Bruna R. De Queiroz, Pierre-Yves Plaçais, Delphine Cerezo, Florence Besse, Thomas Préat, Stéphane Noselli
Regulation of the collagen IV network by the basement membrane protein perlecan is crucial for squamous epithelial cell morphogenesis and organ architecture
Raphaël Bonche, Prune Smolen, Aline Chessel, Séverine Boisivon, Sabrina Pisano, Aaron Voigt, Sébastien Schaub, Pascal Thérond, Sandrine Pizette
Biological effects of the loss of homochirality in a multicellular organism
Agnes Banreti, Shayon Bhattacharya, Frank Wien, Koichi Matsuo, Matthieu Réfrégiers, Cornelia Meinert, Uwe Meierhenrich, Bruno Hudry, Damien Thompson, Stéphane Noselli
An RNA-immunoprecipitation protocol to identify RNAs associated with RNA-binding proteins in cytoplasmic and nuclear Drosophila head fractions
Marjorie Heim, Lauren Blot, Florence Besse
SK2 channels set a signalling hub bolstering CAF-triggered tumourigenic processes in pancreatic cancer
Raphael Rapetti-Mauss, Jérémy Nigri, Camille Berenguier, Pascal Finetti, Sarah Simha Tubiana, Bonnie Labrum, Benoit Allegrini, Bernard Pellissier, Georgios Efthymiou, Zainab Hussain, Corinne Bousquet, Nelson Dusetti, François Bertucci, Hélène Guizouarn, Patricia Melnyk, Franck Borgese, Richard Tomasini, Olivier Soriani
The alternative matrisome: Alternative splicing of ECM proteins in development, homeostasis and tumor progression
Zeinab Rekad, Valerio Izzi, Rijuta Lamba, Delphine Ciais, Ellen Van Obberghen-Schilling
Embryo-scale epithelial buckling forms a propagating furrow that initiates gastrulation
Julien Fierling , Alphy John , Barthélémy Delorme , Alexandre Torzynski , Guy B Blanchard , Claire M Lye , Anna Popkova , Grégoire Malandain , Bénédicte Sanson , Jocelyn Étienne , Philippe Marmottant , Catherine Quilliet , Matteo Rauzi
RNP components condense into repressive RNP granules in the aging brain
Kavya Vinayan Pushpalatha, Mathilde Solyga, Akira Nakamura, Florence Besse
High-Resolution Live Imaging of Axonal RNP Granules in Drosophila Pupal Brain Explants
Caroline Medioni , Jeshlee Vijayakumar , Anne Ephrussi , Florence Besse
Detecting Stress Granules in Drosophila Neurons
Fabienne De Graeve, Nadia Formicola, Kavya Vinayan Pushpalatha, Akira Nakamura, Eric Debreuve, Xavier Descombes, Florence Besse
Plasma Membrane Phosphatidylinositol-4-Phosphate Is Not Necessary for Candida albicans Viability yet Is Key for Cell Wall Integrity and Systemic Infection
Rocio Garcia-Rodas, Hayet Labbaoui, François Orange, Norma Solis, Oscar Zaragoza, Scott G Filler, Martine Bassilana, Robert A Arkowitz
The E3 Ubiquitin Ligase Mindbomb1 controls planar cell polarity-dependent convergent extension movements during zebrafish gastrulation
Vishnu Muraleedharan Saraswathy, Akshai Janardhana Kurup, Priyanka Sharma, Sophie Polès, Morgane Poulain, Maximilian Fürthauer
Live-Imaging of Axonal Cargoes in Drosophila Brain Explants Using Confocal Microscopy
Caroline Medioni, Anne Ephrussi, Florence Besse
Regulation of two-pore-domain potassium TREK channels and their involvement in pain perception and migraine
Pablo Ávalos Prado , Anne-Amandine Chassot , Arnaud Landra-Willm , Guillaume Sandoz
Photopharmacological approaches for dissecting potassium channel physiolog
Stephanie Häfner, Guillaume Sandoz
Germ cell apoptosis is critical to maintain Caenorhabditis elegans offspring viability in stressful environments
Sarah Fausett, Nausicaa Poullet, Clotilde Gimond, Anne Vielle, Michele Bellone, Christian Braendle
Arf6 is necessary for senseless expression in response to wingless signalling during Drosophila wing development
Julien Marcetteau, Tamàs Matusek, Frédéric Luton, Pascal P Thérond
A Myosin Light Chain Is Critical for Fungal Growth Robustness in Candida albicans
Charles Puerner, Antonio Serrano, Rohan S Wakade, Martine Bassilana, Robert A Arkowitz
Infection of C. elegans by Haptoglossa Species Reveals Shared Features in the Host Response to Oomycete Detection
Manish Grover, Michael K Fasseas, Clara Essmann, Kenneth Liu, Christian Braendle, Marie-Anne Félix, Sally L Glockling, Michalis Barkoulas
Retinoic acid signaling is directly activated in cardiomyocytes and protects mouse hearts from apoptosis after myocardial infarction
Fabio Da Silva, Fariba Jian Motamedi, Lahiru Chamara Weerasinghe Arachchige, Amelie Tison, Stephen T Bradford, Jonathan Lefebvre, Pascal Dolle, Norbert B Ghyselinck, Kay D Wagner, Andreas Schedl
Mitotic WNT signalling orchestrates neurogenesis in the developing neocortex
Fabio Da Silva, Kaiqing Zhang, Anneline Pinson, Edoardo Fatti, Michaela Wilsch-Bräuninger, Jessica Herbst, Valerie Vidal, Andreas Schedl, Wieland B Huttner, Christof Niehrs
KLF10 integrates circadian timing and sugar signaling to coordinate hepatic metabolism
Anthony A Ruberto, Aline Gréchez-Cassiau, Sophie Guérin, Luc Martin, Johana S Revel, Mohamed Mehiri, Malayannan Subramaniam, Franck Delaunay, Michèle Teboul
TREK channel activation suppresses migraine pain phenotype
Pablo Ávalos Prado, Arnaud Landra-Willm, Clément Verkest, Aurore Ribera, Anne-Amandine Chassot, Anne Baron, Guillaume Sandoz
Arrest of WNT/β-catenin signaling enables the transition from pluripotent to differentiated germ cells in mouse ovaries
Morgane Le Rolle, Filippo Massa, Pam Siggers, Laurent Turchi, Agnès Loubat, Bon-Kyoung Koo, Hans Clevers, Andy Greenfield, Andreas Schedl, Marie-Christine Chaboissier, Anne-Amandine Chassot
The FibromiR miR-214-3p Is Upregulated in Duchenne Muscular Dystrophy and Promotes Differentiation of Human Fibro-Adipogenic Muscle Progenitors
Nicole Arrighi, Claudine Moratal, Grégoire Savary, Julien Fassy, Nicolas Nottet, Nicolas Pons, Noémie Clément, Sandy Fellah, Romain Larrue, Virginie Magnone, Kevin Lebrigand, Nicolas Pottier, Claude Dechesne, Georges Vassaux, Christian Dani, Pascal Peraldi, Bernard Mari
Model learning to identify systemic regulators of the peripheral circadian clock
Julien Martinelli, Sandrine Dulong, Xiao-Mei Li, Michèle Teboul, Sylvain Soliman, Francis Lévi, François Fages, Annabelle Ballesta
Composite morphogenesis during embryo development
Alphy John, Matteo Rauzi
Adrenal cortex renewal in health and disease
Rodanthi Lyraki, Andreas Schedl
Hherisomes, Hedgehog specialized recycling endosomes, are required for high level Hedgehog signaling and tissue growth
Sandrine Pizette, Tamás Matusek, Bram Herpers, Pascal P Thérond, Catherine Rabouille
A detailed map of coupled circadian clock and cell cycle with qualitative dynamics validation
Adrien Rougny, Loïc Paulevé, Michèle Teboul, Franck Delaunay
Phosphorylated Gβ is a directional cue during yeast gradient tracking
Rashida Abdul-Ganiyu, Leon A Venegas, Xin Wang, Charles Puerner, Robert A Arkowitz, Brian K Kay, David E Stone
The Sexually Dimorphic Adrenal Cortex: Implications for Adrenal Disease
Rodanthi Lyraki, Andreas Schedl
Tyramine induces dynamic RNP granule remodeling and translation activation in the Drosophila brain
Nadia Formicola, Marjorie Heim, Jérémy Dufourt, Anne-Sophie Lancelot, Akira Nakamura, Mounia Lagha, Florence Besse
A two-tier junctional mechanism drives simultaneous tissue folding and extension
Alphy John, Matteo Rauzi
High Dimensional Imaging Mass Cytometry Panel to Visualize the Tumor Immune Microenvironment Contexture
Roxane Elaldi, Patrice Hemon, Luciana Petti, Estelle Cosson, Belinda Desrues, Anne Sudaka, Gilles Poissonnet, Ellen Van Obberghen-Schilling, Jacques-Olivier Pers, Veronique M Braud, Fabienne Anjuère, Aïda Meghraoui-Kheddar
Balancing selection maintains hyper-divergent haplotypes in Caenorhabditis elegans
Daehan Lee, Stefan Zdraljevic, Lewis Stevens, Ye Wang, Robyn E Tanny, Timothy A Crombie, Daniel E Cook, Amy K Webster, Rojin Chirakar, L Ryan Baugh, Mark G Sterken, Christian Braendle, Marie-Anne Félix, Matthew V Rockman, Erik C Andersen
The role of the tumor matrix environment in progression of head and neck cancer
Angélique Saint, Ellen Van Obberghen-Schilling
A fine-tuned azobenzene for enhanced photopharmacology in vivo
Vanessa A Gutzeit, Amanda Acosta-Ruiz, Hermany Munguba, Stephanie Häfner, Arnaud Landra-Willm, Bettina Mathes, Jürgen Mony, Dzianis Yarotski, Karl Börjesson, Conor Liston, Guillaume Sandoz, Joshua Levitz, Johannes Broichhagen
Single-cell transcriptomics reveal temporal dynamics of critical regulators of germ cell fate during mouse sex determination
Chloé Mayère, Yasmine Neirijnck, Pauline Sararols, Chris M Rands, Isabelle Stévant, Françoise Kühne, Anne-Amandine Chassot, Marie-Christine Chaboissier, Emmanouil T Dermitzakis, Serge Nef
The GTPase Rab8 differentially controls the long- and short-range activity of the Hedgehog morphogen gradient by regulating Hedgehog apico-basal distribution
Tanvi Gore, Tamás Matusek, Gisela D'Angelo, Cécile Giordano, Thomas Tognacci, Laurence Lavenant-Staccini, Catherine Rabouille, Pascal P Thérond
Cellular and Supracellular Planar Polarity: A Multiscale Cue to Elongate the Drosophila Egg Chamber
Anna Popkova, Matteo Rauzi, Xiaobo Wang
A dynamic and mosaic basement membrane controls cell intercalation in Drosophila ovaries
Véronique Van De Bor, Vincent Loreau, Marilyne Malbouyres, Delphine Cerezo, Audrey Placenti, Florence Ruggiero, Stéphane Noselli
A single-nucleotide change underlies the genetic assimilation of a plastic trait
Paul Vigne, Clotilde Gimond, Céline Ferrari, Anne Vielle, Johan Hallin, Ania Pino-Querido, Sonia El Mouridi, Laure Mignerot, Christian Frøkjær-Jensen, Thomas Boulin, Henrique Teotónio, Christian Braendle
Fibronectin Extra Domains tune cellular responses and confer topographically distinct features to fibril networks
Georgios Efthymiou, Agata Radwanska, Anca-Ioana Grapa, Stéphanie Beghelli-de la Forest Divonne, Dominique Grall, Sébastien Schaub, Maurice Hattab, Sabrina Pisano, Mallorie Poet, Didier F Pisani, Laurent Counillon, Xavier Descombes, Laure Blanc-Féraud, Ellen Van Obberghen-Schilling
Developmental mechanisms of adrenal cortex formation and their links with adult progenitor populations
Ioannis Oikonomakos, Lahiru Chamara Weerasinghe Arachchige, Andreas Schedl
Selfing is the safest sex for Caenorhabditis tropicalis
Luke M Noble, John Yuen, Lewis Stevens, Nicolas Moya, Riaad Persaud, Marc Moscatelli, Jacqueline L Jackson, Gaotian Zhang, Rojin Chitrakar, L Ryan Baugh, Christian Braendle, Erik C Andersen, Hannah S Seidel, Matthew V Rockman
Pituitary stem cells produce paracrine WNT signals to control the expansion of their descendant progenitor cells
John P Russell, Xinhong Lim, Alice Santambrogio, Val Yianni, Yasmine Kemkem, Bruce Wang, Matthew Fish, Scott Haston, Anaëlle Grabek, Shirleen Hallang, Emily J Lodge, Amanda L Patist, Andreas Schedl, Patrice Mollard, Roel Nusse, Cynthia L Andoniadou
Ubiquitous Selfish Toxin-Antidote Elements in Caenorhabditis Species
Eyal Ben-David, Pinelopi Pliota, Sonya A Widen, Alevtina Koreshova, Tzitziki Lemus-Vergara, Philipp Verpukhovskiy, Sridhar Mandali, Christian Braendle, Alejandro Burga, Leonid Kruglyak
Circulating Hedgehog: a fresh view of a classic morphogen
Elodie Prince, Julien Marcetteau, Pascal P Thérond
KCNE1 is an auxiliary subunit of two distinct ion channel superfamilies
Pablo Ávalos Prado, Stephanie Häfner, Yannick Comoglio, Brigitte Wdziekonski, Christophe Duranton, Bernard Attali, Jacques Barhanin, Guillaume Sandoz
Deciphering and modelling the TGF-β signalling interplays specifying the dorsal-ventral axis of the sea urchin embryo
Swann Floc'hlay, Maria Dolores Molina, Céline Hernandez, Emmanuel Haillot, Morgane Thomas-Chollier, Thierry Lepage, Denis Thieffry
Two different sources of Perlecan cooperate for its function in the basement membrane of the Drosophila wing imaginal disc
Raphaël Bonche, Aline Chessel, Séverine Boisivon, Prune Smolen, Pascal Thérond, Sandrine Pizette
Local retinoic acid signaling directs emergence of the extraocular muscle functional unit
Glenda Evangelina Comai, Markéta Tesařová, Valérie Dupé, Muriel Rhinn, Pedro Vallecillo-García, Fabio da Silva, Betty Feret, Katherine Exelby, Pascal Dollé, Leif Carlsson, Brian Pryce, François Spitz, Sigmar Stricker, Tomáš Zikmund, Jozef Kaiser, James Briscoe, Andreas Schedl, Norbert B Ghyselinck, Ronen Schweitzer, Shahragim Tajbakhsh
The Rosmarinus Bioactive Compound Carnosic Acid Is a Novel PPAR Antagonist That Inhibits the Browning of White Adipocytes
Cécilia Colson, Pierre-Louis Batrow, Nadine Gautier, Nathalie Rochet, Gérard Ailhaud, Franck Peiretti, Ez-Zoubir Amri
Insulin and obesity transform hypothalamic-pituitary-adrenal axis stemness and function in a hyperactive state
Martin Werdermann, Ilona Berger, Laura D Scriba, Alice Santambrogio, Pia Schlinkert, Heike Brendel, Henning Morawietz, Andreas Schedl, Mirko Peitzsch, Aileen J F King, Cynthia L Andoniadou, Stefan R Bornstein, Charlotte Steenblock
WT1 activates transcription of the splice factor kinase SRPK1 gene in PC3 and K562 cancer cells in the absence of corepressor BASP1
Tareg Belali, Chigeru Wodi, Bethany Clark, Man-Kim Cheung, Tim J Craig, Gabrielle Wheway, Nicole Wagner, Kay-Dietrich Wagner, Stefan Roberts, Sean Porazinski, Michael Ladomery
Functions of Wnt and Hedgehog-containing extracellular vesicles in development and disease
Tamás Matusek, Julien Marcetteau, Pascal P Thérond
Mechanical force-induced morphology changes in a human fungal pathogen
Charles Puerner, Nino Kukhaleishvili, Darren Thomson, Sebastien Schaub, Xavier Noblin, Agnese Seminara, Martine Bassilana, Robert A Arkowitz
Cell intercalation in a simple epithelium
Matteo Rauzi
A Natural Mutational Event Uncovers a Life History Trade-Off via Hormonal Pleiotropy
Bénédicte Billard, Paul Vigne, Christian Braendle
Breast cancer mammospheres secrete Adrenomedullin to induce lipolysis and browning of adjacent adipocytes
Martin Paré, Cédric Y Darini, Xi Yao, Bérengère Chignon-Sicard, Samah Rekima, Simon Lachambre, Virginie Virolle, Adriana Aguilar-Mahecha, Mark Basik, Christian Dani, Annie Ladoux