Charlène is a 4th year PhD-student in the lab of Dr. Bruno Hudry, that focuses on sex differences. She dedicated her first years of PhD to unravel the complex role of Y chromosome in sex-specific differences in lifespan and recently completed her outstanding work on that topic by publishing in the prestigious journal of Nature Ecology and Evolution as a co-first author. Currently, Charlène’s research deals with the importance of cellular sex during tumor formation. To better understand why and how tumors are preferentially formed in individuals of a same sex, she uses a genetically-induced tumor model in the adult fly midgut. The midgut tumors only appearing in female flies, Charlène’s ambition is now to elucidate the reasons of this sex-specific tumor formation by identifying the molecular and cellular actors involved. Her promising work will give us more insights about sex differences regarding midgut physiology and cancers.

If you are eager to learn more about Charlène’s topic, don’t hesitate to check her presentation on the iBV common server.

(By Charlène Clot and Margot Noguères)