Prof. Verena Ruprecht will give an exiting course open to all without registration at 8:30AM on Wednesday 26th of March 2025 at the LJAD conference room.

Mechanobiology and error correction in the early embryo

Mechanical forces are key for building the form and functional architecture of an organism. Development is also remarkably robust despite noise and errors at the single cell level. In this lecture I will discuss how tissue architecture and cell shape influence mechanical cell properties and cellular dynamics and how mechano-signalling pathways ensure cell plasticity and error correction during development. I will present quantitative in vitro and in vivo methods that we employ in our lab to investigate these questions and discuss recent findings how actin cytoskeletal dynamics regulate cell clearance to ensure robust embryo development.