Coralie is a 1st year PhD student in Dr.Stéphane Noselli’s team, studying the developmental origin and function of Left-Right asymmetries in Drosophila Brain.

For her first presentation at the PhD club, she discussed her project and the use of new powerful tools such as “Connectomes” to investigate if other asymmetries can be identified in the brain. Connectomes are complete 3D reconstructions of single brains at synaptic resolution. Their recent availability offers the opportunity to explore globally brain Left-Right asymmetry with unprecedented level of detail but also new challenges due to the complexity of the data. She discusses about the different connectomes currently available, their advantages, limitations, and how inconsistent annotations can complicate their comparison.

In addition, she also talks about her first attempts to validate in vivo new, potentially asymmetric, neurons and characterize their asymmetric features, as well as whether the direction of their asymmetry shows a consistent or random population bias.

If you are interested in her work , her presentation is available on the iBV common server.

(By Coralie Mouchet)