From Institute of Neurosciences – Alicante, Spain

will give a seminar entitled :

A body fat sensor in the prothoracic gland controls insect reproductive maturation

Short CV

Education

– D. cum laude, Universidad Autónoma de Madrid, Spain. 1993.
– Sc. in Biology, Universidad de Sevilla, Spain. 1988.

Positions

– Head of the Department of Developmental Neurobiology, Instituto de Neurociencias, UMH-CSIC, Alicante, Spain. 2016-present.
– Full professor from CSIC. Instituto de Neurociencias. 2008-present.
– Vice-director, Instituto de Neurociencias. 2002-2005.
– Research scientist from CSIC, Instituto de Neurociencias. 2006-2008.
– Researcher from CSIC, Instituto de Neurociencias. 2000-2005.
– Postdoctoral fellow, MRC-LMB, Cambridge, UK. 1997-1999.
– Postdoctoral fellow, Universität Zürich, Switzerland. 1993-

Prizes and awards

Eleven prizes and awards for excellence in research, including the IX Francisco Cobos Prize for Biomedicine (2008).

Grants

– Funding grants acquired in 2006–2018 (11). Total: 6,054 million euros.
– Besides this, she is a guarantor researcher (1/10) of the ‘Severo Ochoa Excellence Award’ (SEV-2013-0317) (2013-2018) and (2018-2022)to the Instituto de Neurociencias (~5,500 million euros).

Institutional responsibilities and commission of trust

Dominguez has been invited to participate in a range of high-level scientific advisory boards and expert panels at national and international institutes including the Scientific Advisor for the Alexander von Humboldt Foundation (2015), and she is a member of 3 Editorial Boards.

Invited conferences

Invited speaker at 72 lectures, of which about 64% were abroad (15 countries), including recent Plenary lectures in 56^th ‘Annual Drosophila Research Conference’, Chicago, US (2015).

Selected publications

– Villegas SN, Gombos R, García-López L, Gutiérrez-Pérez I, García-Castillo J, Vallejo DM, Da Ros V, Ballesta-Illán E, Mihály J, Dominguez M^§. PI3K/Akt Cooperates with Oncogenic Notch by Inducing Nitric Oxide-Dependent Inflammation. Cell Rep. 2018 Mar 6; 22(10):2541-2549. doi: 10.1016/j.celrep.2018.02.049.
– Vallejo DM, Juarez-Carreño S, Bolivar J, Morante J, Dominguez M^§. A brain circuit that synchronizes growth and maturation revealed through Dilp8 binding to Lgr3. Science. 2015 Nov 13;350(6262):aac6767. doi: 10.1126/science.aac6767. Epub 2015 Oct 1.
– Garelli A, Gontijo A, Miguela V, Caparros E, Dominguez M. Imaginal discs secrete insulin-like peptide 8 to mediate plasticity of growth and maturation time. Science. 2012 May 12;336(6081):579-582. doi: 10.1126/science.1216735. PMID: 22556250.
– Antonello ZA, Reiff T, Ballesta-Illán E, Dominguez M. Robust intestinal homeostasis relies on cellular plasticity in enteroblasts mediated by miR-8-Escargot switch. EMBO J. 2015 Aug 4;34(15):2025-2041. doi: 10.15252/embj.201591517.
– Reiff T, Jacobson J, Cognigni P, Antonello ZA, Ballesta-Illan E, Tan KT, Yew JY, Dominguez M, Miguel-Aliaga I^§. Endocrine remodelling of the adult intestine sustains reproduction in Drosophila. Elife. 2015 Jul 28;4:e06930. doi: 10.7554/eLife.06930. PMID: 26216039.
– Morante J, Vallejo DM, Desplan C, Dominguez M. Conserved miR-8/miR-200 defines a glial niche that controls neuroepithelial expansion and neuroblast transition. Dev Cell. 2013 Oct 28;27(2):174-187. doi: 10.1016/j.devcel.2013.09.018. Epub 2013 Oct 17.
– Vallejo DM, Caparrós E, Dominguez M.Targeting Notch signalling by the conserved miR8/200 microRNA family in development and cancer cells. EMBO J. 2011 Feb 16;30(4):756-769. Epub 2011 Jan 11. PMID: 21224847
– Ferres-Marco D, Gutierrez I, Vallejo DM, Bolivar J, Gutierrez-Aviñó FJ, Dominguez M. Epigenetic silencers and Notch collaborate to promote malignant tumours by Rb silencing. Nature. 2006 Jan 26;439(7075):430-436.