From: Université de Liège – GIGA

Will give a seminar entitled:

Regulation of Cerebral Cortex Morphogenesis by Migrating Cells – Evo Devo Perspectives

The work of Laurent Nguyen is based on deciphering the molecular controls of cerebral cortical neurogenesis and unraveling the mechanisms of neuron migration and microcircuit integration in health and disease.

Laurent Nguyen got very recently an ERC synergy grant.

Some of his main recent publications:
– Lepiemme, F., Stoufflet, J., Javier-Torrent, M., Mazzucchelli, G., Silva, C.*, and, Nguyen, L.*: Oligodendrocyte precursors guide interneuron migration by unidirectional contact repulsion. Science (2022) 376 (6595)
– Even, A., * Morelli, G., * Turchetto, S.,* Shilian, M., Le Bail, R., Laguesse, S., Krusy, N., Brisker, A., Brandis, A., Inbar, S., Chariot, A., Saudou, F., Dietrich, P., Dragatsis, I., Brône, B., Broix, L., Rigo, J.-M., Weil, M., * and Nguyen, L. *:  ATP-Citrate lyase promotes axonal transport across species. Nat Commun (2021) 2(1):5878. doi: 10.1038/s41467-021-25786-y
– Silva, C.G., Peyre, E., Adhikari, M. H., Tielens, S., Tanco, S., Van Damme, P., Magno, L., Krusy, N., Agirman, G., Magiera, M. M., Kessaris, N., Malgrange, B., Andrieux, A., Janke, C., and Nguyen, L. : Cell-intrinsic control of interneuron migration drives cortical morphogenesis. Cell (2018), 172(5): 1063-78
– Gladwyn-Ng, I., Cordon Barris, L., Alfano, C., Creppe, C., Couderc, T., Morelli, G., Thelen, N., America, M., Bessières, B., Ench-Razavi, F., Bonnière, M., Susuki, I., Flamand, M., Vanderhaeghen, P., Lecuit, M., and Nguyen, L . : Stress-induced unfolded protein response contributes to Zika virus-associated microcephaly. Nature Neuroscience (2018), 21(1):63-71
– Stoufflet, J.*, Tielens, S.*, and Nguyen, L. : Shaping the cerebral cortex by cellular crosstalk. Cell (2023) 186 (13): 2733-2747
– Lepiemme, F., Silva, C., and Nguyen, L. *: Time lapse recording of cortical interneuron migration in mouse organotypic brain slices and explants. Star Protocols (2021) 2(2):100467
– Broix, L., Silvia Turchetto, S., and Nguyen, L. : Coordination between transport and local translation in neurons. Trends in Cell Biol (2021) 44(2): 110-121

Speaker website