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X-ORIGINAL-URL:http://ibv.unice.fr
X-WR-CALDESC:Events for iBV
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DTSTART:20200329T010000
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DTSTART;TZID=Europe/Paris:20200221T110000
DTEND;TZID=Europe/Paris:20200221T110000
DTSTAMP:20260416T220901
CREATED:20200212T125750Z
LAST-MODIFIED:20200212T125750Z
UID:8768-1582282800-1582282800@ibv.unice.fr
SUMMARY:Olivier DAVID
DESCRIPTION:From Grenoble Institut Neurosciences (GIN) \nwill give a seminar entitled: \nBrain electrical stimulation: a clinical tool that stimulates fundamental research  \n  \n  \nThis talk is about how in vivo electrophysiology can be used to study large scale brain networks using various examples. I will first remind very general principles of brain’s functional organisation at a large scale. I will then illustrate how clinical techniques such as deep brain stimulation clearly demonstrate functional specialization of both cortical and subcortical areas. Examples will consider Parkinson’s disease\, obsessive compulsive disorders and epilepsy. On a more fundamental aspect\, I will then show how brief electrical pulses allow to reconstruct brain circuitry and local neuronal properties in human (Trebaul et al\, 2018). More preliminary data will also be presented on how we are currently translating this stimulation technique for interrogating mechanisms of action of drug compounds in vivo in rodents. Finally\, I will present the recent work we did to unravel from electrophysiology a new subcortical pathway for pain processing in rodent which was motivated by chronic pain often experienced by Parkinsonian patients (Pautrat et al\, 2018). \n  \nReferences: \nTrebaul et al.\, Probabilistic functional tractography of the human cortex revisited\, Neuroimage. 2018 Nov 1\,181:414-429 \nPautrat et al.\, Revealing a novel nociceptive network that links the subthalamic nucleus to pain processing. Elife. 2018 Aug 28\,7. pii: e36607
URL:http://ibv.unice.fr/event/olivier-david/
LOCATION:Salle de Conférences\, Centre de Biochimie\, 28 avenue Valrose\, Faculté des Sciences\, Parc Valrose\, Nice\, 06100\, France
CATEGORIES:Seminars
ORGANIZER;CN="Mich%C3%A8le%20STUDER":MAILTO:studer@unice.fr
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