BEGIN:VCALENDAR
VERSION:2.0
PRODID:-//iBV - ECPv5.8.1//NONSGML v1.0//EN
CALSCALE:GREGORIAN
METHOD:PUBLISH
X-WR-CALNAME:iBV
X-ORIGINAL-URL:http://ibv.unice.fr
X-WR-CALDESC:Events for iBV
BEGIN:VTIMEZONE
TZID:Europe/Paris
BEGIN:DAYLIGHT
TZOFFSETFROM:+0100
TZOFFSETTO:+0200
TZNAME:CEST
DTSTART:20260329T010000
END:DAYLIGHT
BEGIN:STANDARD
TZOFFSETFROM:+0200
TZOFFSETTO:+0100
TZNAME:CET
DTSTART:20261025T010000
END:STANDARD
END:VTIMEZONE
BEGIN:VEVENT
DTSTART;TZID=Europe/Paris:20261005T110000
DTEND;TZID=Europe/Paris:20261005T110000
DTSTAMP:20260930T191503
CREATED:20260930T022817Z
LAST-MODIFIED:20260930T022817Z
UID:15799-1791198000-1791198000@ibv.unice.fr
SUMMARY:Michaël OHANNA
DESCRIPTION:From: C3M\, Université Côte d’Azur \n  \nWill give a seminar entitled: \n\n  \nNuclear deformation as a driver of melanoma phenotypic plasticity \n\nMelanoma cells display remarkable phenotypic plasticity\, allowing them to switch between proliferative\, invasive and therapy-tolerant states. While these transitions are often described through transcriptional and epigenetic programs\, emerging evidence suggests that nuclear architecture and mechanical constraints may also shape melanoma cell behavior. In this seminar\, I will discuss how nuclear deformation and nuclear envelope remodeling\, with a focus on lamin-associated mechanisms\, may contribute to melanoma invasive adaptation. I will present preliminary data linking nuclear mechanical features to melanoma cell-state plasticity and discuss how this emerging axis could open new perspectives on tumour heterogeneity and therapeutic resistance. \n 
URL:http://ibv.unice.fr/event/michael-ohanna/
LOCATION:Laboratoire J.-A. Dieudonné\, Salle de Conférence\, Parc Valrose\, Nice\, 06100\, France
CATEGORIES:Seminars
ATTACH;FMTTYPE=image/jpeg:http://ibv.unice.fr/wp-content/uploads/Michaël-Ohanna.jpg
ORGANIZER;CN="Matteo%20RAUZI":MAILTO:mrauzi@unice.fr
END:VEVENT
END:VCALENDAR