Andreas Schedl
  Team : Schedl Andreas
  activité : Chef d`quipe
  Localisation : Centre de Biochimie
  Tel: +33 492076401
  Fax : +33 492076475

2009 Award of the French kidney foundation (Fondation du Rein)

2003 Avenir (INSERM, France)

2002 Philippe Leverhulme Prize (UK)

2001 EMBO Young Investigator Programme


A knock-in mouse line conditionally expressing the tumor suppressor WTX/AMER1. - 2017 - Genesis (New York, N.Y. : 2000) - 55
Boutet A, Comai G, Charlet A, Jian Motamedi F, Dhib H, Bandiera R, and Schedl,A

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3. - 2017 - Cell reports - 20 P1745-1754
Da Silva F, Rocha AS, Motamedi FJ, Massa F, Basboga C, Morrison H, Wagner KD, and Schedl,A

Amplification of R-spondin1 signaling induces granulosa cell fate defects and cancers in mouse adult ovary. - 2017 - Oncogene - 36 P208-218
De Cian MC, Pauper E, Bandiera R, Vidal VP, Sacco S, Gregoire EP, Chassot AA, Panzolini C, Wilhelm D, Pailhoux E, Youssef SA, de Bruin A, Teerds K, Schedl A, Gillot I, and Chaboissier,MC

PKA inhibits WNT signalling in adrenal cortex zonation and prevents malignant tumour development. - 2016 - Nature communications - 7 P12751
Drelon C, Berthon A, Sahut-Barnola I, Mathieu M, Dumontet T, Rodriguez S, Batisse-Lignier M, Tabbal H, Tauveron I, Lefranois-Martinez AM, Pointud JC, Gomez-Sanchez CE, Vainio S, Shan J, Sacco S, Schedl A, Stratakis CA, Martinez A, and Val,P

Identifying Direct Downstream Targets: WT1 ChIP-Seq Analysis. - 2016 - Methods in molecular biology (Clifton, N.J.) - 1467 P177-88
da Silva F, Massa F, and Schedl,A

Repression of CMIP transcription by WT1 is relevant to podocyte health. - 2016 - Kidney international - 90 P1298-1311
Moktefi A, Zhang SY, Vachin P, Ory V, Henique C, Audard V, Rucker-Martin C, Gouadon E, Eccles M, Schedl A, Heidet L, Ollero M, Sahali D, and Pawlak,A

The adrenal capsule is a signaling center controlling cell renewal and zonation through Rspo3. - 2016 - Genes & development - 30 P1389-94
Vidal V, Sacco S, Rocha AS, da Silva F, Panzolini C, Dumontet T, Doan TM, Shan J, Rak-Raszewska A, Bird T, Vainio S, Martinez A, and Schedl,A

Sox9 Activation Highlights a Cellular Pathway of Renal Repair in the Acutely Injured Mammalian Kidney. - 2015 - Cell reports - 12 P1325-38
Kumar S, Liu J, Pang P, Krautzberger AM, Reginensi A, Akiyama H, Schedl A, Humphreys BD, and McMahon,AP

Alternatively spliced isoforms of WT1 control podocyte-specific gene expression. - 2015 - Kidney international - 88 P321-31
Lefebvre J, Clarkson M, Massa F, Bradford ST, Charlet A, Buske F, Lacas-Gervais S, Schulz H, Gimpel C, Hata Y, Schaefer F, and Schedl,A

Steroidogenic organ development and homeostasis: A WT1-centric view. - 2015 - Molecular and cellular endocrinology - 408 P145-55
Bandiera R, Sacco S, Vidal VP, Chaboissier MC, and Schedl,A

The Angiocrine Factor Rspondin3 Is a Key Determinant of Liver Zonation. - 2015 - Cell reports - 13 P1757-64
Rocha AS, Vidal V, Mertz M, Kendall TJ, Charlet A, Okamoto H, and Schedl,A

WT1 controls antagonistic FGF and BMP-pSMAD pathways in early renal progenitors. - 2014 - Nature communications - 5 P4444
Motamedi FJ, Badro DA, Clarkson M, Lecca MR, Bradford ST, Buske FA, Saar K, Hìbner N, Brìndli AW, and Schedl,A

Visceral and subcutaneous fat have different origins and evidence supports a mesothelial source. - 2014 - Nature cell biology - 16 P367-75
Chau YY, Bandiera R, Serrels A, Martìnez-Estrada OM, Qing W, Lee M, Slight J, Thornburn A, Berry R, McHaffie S, Stimson RH, Walker BR, Chapuli RM, Schedl A, and Hastie,N

WT1 Maintains Adrenal-Gonadal Primordium Identity and Marks a Population of AGP-like Progenitors within the Adrenal Gland. - 2013 - Dev Cell - 27 P5-18
Bandiera R, Vidal VP, Motamedi FJ, Clarkson M, Sahut-Barnola I, von Gise A, Pu WT, Hohenstein P, Martinez A, and Schedl,A

WNT4 and RSPO1 together are required for cell proliferation in the early mouse gonad. - 2012 - Development - 139 P4461-72
Chassot AA, Bradford ST, Auguste A, Gregoire EP, Pailhoux E, de Rooij DG, Schedl A, and Chaboissier,MC

Testicular differentiation occurs in absence of R-spondin1 and Sox9 in mouse sex reversals. - 2012 - PLoS Genet - 8 Pe1003170
Lavery R, Chassot AA, Pauper E, Gregoire EP, Klopfenstein M, de Rooij DG, Mark M, Schedl A, Ghyselinck NB, and Chaboissier,MC

A novel approach to selectively target neuronal subpopulations reveals genetic pathways that regulate tangential migration in the vertebrate hindbrain. - 2011 - PLoS Genet - 7 Pe1002099
Benzing K, Flunkert S, Schedl A, and Engelkamp,D

The podocyte protein nephrin is required for cardiac vessel formation. - 2011 - Hum Mol Genet - 20 P2182-94
Wagner N, Morrison H, Pagnotta S, Michiels JF, Schwab Y, Tryggvason K, Schedl A, and Wagner,KD

SOX9 controls epithelial branching by activating RET effector genes during kidney development. - 2011 - Hum Mol Genet - 20 P1143-53
Reginensi A, Clarkson M, Neirijnck Y, Lu B, Ohyama T, Groves AK, Sock E, Wegner M, Costantini F, Chaboissier MC, and Schedl,A

Cbx2, a polycomb group gene, is required for Sry gene expression in mice. - 2011 - Endocrinology - 153 P913-24
Katoh-Fukui Y, Miyabayashi K, Komatsu T, Owaki A, Baba T, Shima Y, Kidokoro T, Kanai Y, Schedl A, Wilhelm D, Koopman P, Okuno Y, and Morohashi,K

Novel perspectives for investigating congenital anomalies of the kidney and urinary tract (CAKUT). - 2011 - Nephrol Dial Transplant - 26 P3843-51
Renkema KY, Winyard PJ, Skovorodkin IN, Levtchenko E, Hindryckx A, Jeanpierre C, Weber S, Salomon R, Antignac C, Vainio S, Schedl A, Schaefer F, Knoers NV, and Bongers,EM

COUP-TFI promotes radial migration and proper morphology of callosal projection neurons by repressing Rnd2 expression. - 2011 - Development - 138 P4685-97
Alfano C, Viola L, Heng JI, Pirozzi M, Clarkson M, Flore G, De Maio A, Schedl A, Guillemot F, and Studer,M

Expression patterns of the Wtx/Amer gene family during mouse embryonic development. - 2010 - Dev Dyn - 239 P1867-78
Comai G, Boutet A, Neirijnck Y, and Schedl,A

The WTX/AMER1 gene family: evolution, signature and function. - 2010 - BMC Evol Biol - 10 P280
Boutet A, Comai G, and Schedl,A

A cell-autonomous role for WT1 in regulating Sry in vivo. - 2009 - Hum Mol Genet - 18 P3429-38
Bradford ST, Wilhelm D, Bandiera R, Vidal V, Schedl A, and Koopman,P

Renal abnormalities and their developmental origin. - 2007 - Nat Rev Genet - 8 P791-802

An inducible mouse model for PAX2-dependent glomerular disease: insights into a complex pathogenesis. - 2006 - Curr Biol - 16 P793-800
Wagner KD, Wagner N, Guo JK, Elger M, Dallman MJ, Bugeon L, and Schedl,A

R-spondin1 is essential in sex determination, skin differentiation and malignancy. - 2006 - Nat Genet - 38 P1304-9
Parma P, Radi O, Vidal V, Chaboissier MC, Dellambra E, Valentini S, Guerra L, Schedl A, and Camerino,G

Sox9 is essential for outer root sheath differentiation and the formation of the hair stem cell compartment. - 2005 - Curr Biol - 15 P1340-51
Vidal VP, Chaboissier MC, Ltzkendorf S, Cotsarelis G, Mill P, Hui CC, Ortonne N, Ortonne JP, and Schedl,A

Functional analysis of Sox8 and Sox9 during sex determination in the mouse. - 2004 - Development - 131 P1891-901
Chaboissier MC, Kobayashi A, Vidal VI, Ltzkendorf S, van de Kant HJ, Wegner M, de Rooij DG, Behringer RR, and Schedl,A

Sox9 induces testis development in XX transgenic mice. - 2001 - Nat Genet - 28 P216-7
Vidal VP, Chaboissier MC, de Rooij DG, and Schedl,A

Loss of caveolae, vascular dysfunction, and pulmonary defects in caveolin-1 gene-disrupted mice. - 2001 - Science - 293 P2449-52
Drab M, Verkade P, Elger M, Kasper M, Lohn M, Lauterbach B, Menne J, Lindschau C, Mende F, Luft FC, Schedl A, Haller H, and Kurzchalia,TV



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