Kay Dietrich Wagner
     
  Team : Wagner Kay
  activité : Chef d`équipe
  Localisation : Tour Pasteur
  Tel: +33 493377665
  Fax : -
  e-mail: kwagner@unice.fr
     
Awards

2015 Grand Prix Cancérologie Fondation Simone et Cino del Duca, Academie des sciences

2007 INSERM AVENIR

2007 Du Bois-Reymond-Prize, German Physiological Society

2003 EMBO Long-term Fellow

1998 Robert-Koch-Prize, Charité, Germany

Publications

Small RNA-directed epigenetic programming of embryonic stem cell cardiac differentiation. - 2017 - Scientific reports - 7 P41799
Ghanbarian H, Wagner N, Michiels JF, Cuzin F, Wagner KD, and Rassoulzadegan,M

CDK9 regulates apoptosis of myoblast cells by modulation of microRNA-1 expression. - 2017 - Journal of cellular biochemistry
Tarhriz V, Wagner KD, Masoumi Z, Molavi O, Hejazi MS, and Ghanbarian,H

The differential spatiotemporal expression pattern of shelterin genes throughout lifespan. - 2017 - Aging - 9 P1219-1232
Wagner KD, Ying Y, Leong W, Jiang J, Hu X, Chen Y, Michiels JF, Lu Y, Gilson E, Wagner N, and Ye,J

Coronary Artery Formation Is Driven by Localized Expression of R-spondin3. - 2017 - Cell reports - 20 P1745-1754
Da Silva F, Rocha AS, Motamedi FJ, Massa F, Basboga C, Morrison H, Wagner KD, and Schedl,A

RNA activation of the VEGF promoter by dsRNA and hypoxia: Role of non-coding VEGF promoter transcripts. - 2016 - Molecular and cellular biology
Lopez P, Wagner KD, Hofman P, and Van Obberghen,E

Inducible Conditional Vascular-Specific Overexpression of Peroxisome Proliferator-Activated Receptor Beta/Delta Leads to Rapid Cardiac Hypertrophy. - 2016 - PPAR research - 2016 P7631085
Wagner KD, Vukolic A, Baudouy D, Michiels JF, and Wagner,N

Extracardiac septum transversum/proepicardial endothelial cells pattern embryonic coronary arterio-venous connections. - 2016 - Proceedings of the National Academy of Sciences of the United States of America - 113 P656-61
Cano E, Carmona R, Ruiz-Villalba A, Rojas A, Chau YY, Wagner KD, Wagner N, Hastie ND, Muñoz-Chápuli R, and Pérez-Pomares,JM

Dnmt2/Trdmt1 as Mediator of RNA Polymerase II Transcriptional Activity in Cardiac Growth. - 2016 - PloS one - 11 Pe0156953
Ghanbarian H, Wagner N, Polo B, Baudouy D, Kiani J, Michiels JF, Cuzin F, Rassoulzadegan M, and Wagner,KD

The Telomeric Protein TRF2 Regulates Angiogenesis by Binding and Activating the PDGFRβ Promoter. - 2014 - Cell reports - 9 P1047-60
El Maì¯ M, Wagner KD, Michiels JF, Ambrosetti D, Borderie A, Destree S, Renault V, Djerbi N, Giraud-Panis MJ, Gilson E, and Wagner,N

The Wilms' tumour suppressor Wt1 is a major regulator of tumour angiogenesis and progression. - 2014 - Nature communications - 5 P5852
Wagner KD, Cherfils-Vicini J, Hosen N, Hohenstein P, Gilson E, Hastie ND, Michiels JF, and Wagner,N

The podocyte protein nephrin is required for cardiac vessel formation. - 2011 - Human molecular genetics - 20 P2182-94
Wagner N, Morrison H, Pagnotta S, Michiels JF, Schwab Y, Tryggvason K, Schedl A, and Wagner,KD

Peroxisome proliferator-activated receptor ?/? (PPAR?/?) is highly expressed in liposarcoma and promotes migration and proliferation. - 2011 - The Journal of pathology - 224 P575-88
Wagner KD, Benchetrit M, Bianchini L, Michiels JF, and Wagner,N

Mouse knockout of the cholesterogenic cytochrome P450 lanosterol 14alpha-demethylase (Cyp51) resembles Antley-Bixler syndrome. - 2011 - The Journal of biological chemistry - 286 P29086-97
Keber R, Motaln H, Wagner KD, Debeljak N, Rassoulzadegan M, Ačimovič J, Rozman D, and Horvat,S

Peroxisome proliferator-activated receptor β/δ (PPARβ/δ) is highly expressed in liposarcoma and promotes migration and proliferation. - 2011 - The Journal of pathology - 224 P575-88
Wagner KD, Benchetrit M, Bianchini L, Michiels JF, and Wagner,N

The podocyte protein nephrin is required for cardiac vessel formation. - 2011 - Human molecular genetics - 20 P2182-94
Wagner N, Morrison H, Pagnotta S, Michiels JF, Schwab Y, Tryggvason K, Schedl A, and Wagner,KD

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions. - 2010 - Pharmacology & therapeutics - 125 P423-35
Wagner KD, and Wagner,N

Enhanced L-type calcium currents in cardiomyocytes from transgenic rats overexpressing SERCA2a. - 2010 - Experimental and clinical cardiology - 15 Pe109-15
Kamkin A, Kiseleva I, Theres H, Eulert-Grehn JJ, Wagner KD, Scholz H, and Vetter,R

Peroxisome proliferator-activated receptor beta/delta (PPARbeta/delta) acts as regulator of metabolism linked to multiple cellular functions. - 2010 - Pharmacology & therapeutics - 125 P423-35
Wagner KD, and Wagner,N

Role of the Wilms' tumour transcription factor, Wt1, in blood vessel formation. - 2009 - Pflugers Archiv : European journal of physiology - 458 P315-23
Scholz H, Wagner KD, and Wagner,N

Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin. - 2009 - Cardiovascular research - 83 P61-71
Wagner N, Jehl-Piétri C, Lopez P, Murdaca J, Giordano C, Schwartz C, Gounon P, Hatem SN, Grimaldi P, and Wagner,KD

The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth. - 2009 - Development (Cambridge, England) - 136 P3647-55
Grandjean V, Gounon P, Wagner N, Martin L, Wagner KD, Bernex F, Cuzin F, and Rassoulzadegan,M

The miR-124-Sox9 paramutation: RNA-mediated epigenetic control of embryonic and adult growth. - 2009 - Development (Cambridge, England) - 136 P3647-55
Grandjean V, Gounon P, Wagner N, Martin L, Wagner KD, Bernex F, Cuzin F, and Rassoulzadegan,M

Peroxisome proliferator-activated receptor beta stimulation induces rapid cardiac growth and angiogenesis via direct activation of calcineurin. - 2009 - Cardiovascular research - 83 P61-71
Wagner N, Jehl-Piétri C, Lopez P, Murdaca J, Giordano C, Schwartz C, Gounon P, Hatem SN, Grimaldi P, and Wagner,KD

A novel Wilms' tumor 1 gene mutation in a child with severe renal dysfunction and persistent renal blastema. - 2008 - Pediatric nephrology (Berlin, Germany) - 23 P1445-53
Wagner N, Wagner KD, Afanetti M, Nevo F, Antignac C, Michiels JF, Schedl A, and Berard,E

The Wilms' tumor suppressor WT1 is associated with melanoma proliferation. - 2008 - Pflugers Archiv : European journal of physiology - 455 P839-47
Wagner N, Panelos J, Massi D, and Wagner,KD

RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse. - 2008 - Developmental cell - 14 P962-9
Wagner KD, Wagner N, Ghanbarian H, Grandjean V, Gounon P, Cuzin F, and Rassoulzadegan,M

The Wilms' tumour suppressor WT1 is involved in endothelial cell proliferation and migration: expression in tumour vessels in vivo. - 2008 - Oncogene - 27 P3662-72
Wagner N, Michiels JF, Schedl A, and Wagner,KD

RNA induction and inheritance of epigenetic cardiac hypertrophy in the mouse. - 2008 - Developmental cell - 14 P962-9
Wagner KD, Wagner N, Ghanbarian H, Grandjean V, Gounon P, Cuzin F, and Rassoulzadegan,M

The Wilms tumor suppressor Wt1 promotes cell adhesion through transcriptional activation of the alpha4integrin gene. - 2006 - The Journal of biological chemistry - 281 P31930-9
Kirschner KM, Wagner N, Wagner KD, Wellmann S, and Scholz,H

An inducible mouse model for PAX2-dependent glomerular disease: insights into a complex pathogenesis. - 2006 - Current biology : CB - 16 P793-800
Wagner KD, Wagner N, Guo JK, Elger M, Dallman MJ, Bugeon L, and Schedl,A

Intermediate filament protein nestin is expressed in developing kidney and heart and might be regulated by the Wilms' tumor suppressor Wt1. - 2006 - American journal of physiology. Regulatory, integrative and comparative physiology - 291 PR779-87
Wagner N, Wagner KD, Scholz H, Kirschner KM, and Schedl,A

An inducible mouse model for PAX2-dependent glomerular disease: insights into a complex pathogenesis. - 2006 - Current biology : CB - 16 P793-800
Wagner KD, Wagner N, Guo JK, Elger M, Dallman MJ, Bugeon L, and Schedl,A

The Wilms tumor suppressor Wt1 promotes cell adhesion through transcriptional activation of the alpha4integrin gene. - 2006 - The Journal of biological chemistry - 281 P31930-9
Kirschner KM, Wagner N, Wagner KD, Wellmann S, and Scholz,H

A splice variant of the Wilms' tumour suppressor Wt1 is required for normal development of the olfactory system. - 2005 - Development (Cambridge, England) - 132 P1327-36
Wagner N, Wagner KD, Hammes A, Kirschner KM, Vidal VP, Schedl A, and Scholz,H

Coronary vessel development requires activation of the TrkB neurotrophin receptor by the Wilms' tumor transcription factor Wt1. - 2005 - Genes & development - 19 P2631-42
Wagner N, Wagner KD, Theres H, Englert C, Schedl A, and Scholz,H

The major podocyte protein nephrin is transcriptionally activated by the Wilms' tumor suppressor WT1. - 2004 - Journal of the American Society of Nephrology : JASN - 15 P3044-51
Wagner N, Wagner KD, Xing Y, Scholz H, and Schedl,A

The complex life of WT1. - 2003 - Journal of cell science - 116 P1653-8
Wagner KD, Wagner N, and Schedl,A

The Wilms' tumor suppressor Wt1 encodes a transcriptional activator of the class IV POU-domain factor Pou4f2 (Brn-3b). - 2003 - Gene - 305 P217-23
Wagner KD, Wagner N, Schley G, Theres H, and Scholz,H

Oxygen-regulated expression of the Wilms' tumor suppressor Wt1 involves hypoxia-inducible factor-1 (HIF-1). - 2003 - FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 17 P1364-6
Wagner KD, Wagner N, Wellmann S, Schley G, Bondke A, Theres H, and Scholz,H

1,25-dihydroxyvitamin D3-induced apoptosis of retinoblastoma cells is associated with reciprocal changes of Bcl-2 and bax. - 2003 - Experimental eye research - 77 P1-9
Wagner N, Wagner KD, Schley G, Badiali L, Theres H, and Scholz,H

Characterization of stretch-activated ion currents in isolated atrial myocytes from human hearts. - 2003 - Pflügers Archiv : European journal of physiology - 446 P339-46
Kamkin A, Kiseleva I, Wagner KD, Bohm J, Theres H, Gì¼nther J, and Scholz,H

Mechanically induced potentials in atrial fibroblasts from rat hearts are sensitive to hypoxia/reoxygenation. - 2003 - Pflügers Archiv : European journal of physiology - 446 P169-74
Kamkin A, Kiseleva I, Wagner KD, Lozinsky I, Gì¼nther J, and Scholz,H

The long-lasting impact of postnatal neuropeptide Y. - 2003 - American journal of physiology. Regulatory, integrative and comparative physiology - 284 PR1382-3
Wagner KD, and Scholz,H

The complex life of WT1. - 2003 - Journal of cell science - 116 P1653-8
Wagner KD, Wagner N, and Schedl,A

The Wilms' tumor suppressor Wt1 is expressed in the coronary vasculature after myocardial infarction. - 2002 - FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 16 P1117-9
Wagner KD, Wagner N, Bondke A, Nafz B, Flemming B, Theres H, and Scholz,H

The Wilms' tumor gene Wt1 is required for normal development of the retina. - 2002 - The EMBO journal - 21 P1398-405
Wagner KD, Wagner N, Vidal VP, Schley G, Wilhelm D, Schedl A, Englert C, and Scholz,H

The Wilms' tumor suppressor Wt1 is associated with the differentiation of retinoblastoma cells. - 2002 - Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research - 13 P297-305
Wagner N, Wagner KD, Schley G, Coupland SE, Heimann H, Grantyn R, and Scholz,H

Transgenic overexpression of the sarcoplasmic reticulum Ca2+ATPase improves reticular Ca2+ handling in normal and diabetic rat hearts. - 2002 - FASEB journal : official publication of the Federation of American Societies for Experimental Biology - 16 P1657-9
Vetter R, Rehfeld U, Reissfelder C, Weiss W, Wagner KD, Gì¼nther J, Hammes A, Tschì¶pe C, Dillmann W, and Paul,M

Decreased susceptibility of cardiac function to hypoxia-reoxygenation in renin-angiotensinogen transgenic rats. - 2002 - American journal of physiology. Regulatory, integrative and comparative physiology - 283 PR153-60
Wagner KD, Essmann V, Mydlak K, Wirth M, Gmehling G, Bohlender J, Stauss HM, Gì¼nther J, Schimke I, and Scholz,H

A possible role for atrial fibroblasts in postinfarction bradycardia. - 2002 - American journal of physiology. Heart and circulatory physiology - 282 PH842-9
Kamkin A, Kiseleva I, Wagner KD, Pylaev A, Leiterer KP, Theres H, Scholz H, Gì¼nther J, and Isenberg,G

Time-dependent changes of the susceptibility of cardiac contractile function to hypoxia-reoxygenation after myocardial infarction in rats. - 2002 - Molecular and cellular biochemistry - 241 P125-33
Wagner KD, Gmehling G, Gunther J, Theres H, Mydlak K, Schimke I, and Scholz,H

Activation of vitamin D receptor by the Wilms' tumor gene product mediates apoptosis of renal cells. - 2001 - Journal of the American Society of Nephrology : JASN - 12 P1188-96
Wagner KD, Wagner N, Sukhatme VP, and Scholz,H

Contractile function of rat myocardium is less susceptible to hypoxia/reoxygenation after acute infarction. - 2001 - Molecular and cellular biochemistry - 228 P49-55
Wagner KD, Gmehling G, Gì¼nther J, Stauss HM, Mydlak K, Theres H, Scholz H, and Schimke,I

Myocardial adrenergic dysfunction in rats with transgenic, human renin-dependent hypertension. - 2001 - Journal of hypertension - 19 P1453-63
Bohlender J, Hildenbrand U, Wagner KD, Gì¼nther J, Hempel P, Schlegel WP, Luft FC, Krause EG, and Bartel,S

Mechanically induced potentials in rat atrial fibroblasts depend on actin and tubulin polymerisation. - 2001 - Pflügers Archiv : European journal of physiology - 442 P487-97
Kamkin A, Kiseleva I, Wagner KD, Scholz H, Theres H, Kazanski V, Lozinsky I, Gì¼nther J, and Isenberg,G

An abnormal response of retinoblastoma cells (Y-79) to neurotrophins. - 2000 - Investigative ophthalmology & visual science - 41 P1932-9
Wagner N, Wagner KD, Sefton M, Rodríguez-Tébar A, and Grantyn,R

Mechanoelectric feedback after left ventricular infarction in rats. - 2000 - Cardiovascular research - 45 P370-8
Kiseleva I, Kamkin A, Wagner KD, Theres H, Ladhoff A, Scholz H, Gì¼nther J, and Lab,MJ

Mechano-electric feedback in right atrium after left ventricular infarction in rats. - 2000 - Journal of molecular and cellular cardiology - 32 P465-77
Kamkin A, Kiseleva I, Wagner KD, Leiterer KP, Theres H, Scholz H, Gì¼nther J, and Lab,MJ

Oxygen radical system in chronic infarcted rat heart: the effect of combined beta blockade and ACE inhibition. - 2000 - Journal of cardiovascular pharmacology - 35 P708-15
Theres H, Wagner KD, Schulz S, Strube S, Leiterer KP, Romberg D, Gì¼nther J, Scholz H, Baumann G, and Schimke,I

An abnormal response of retinoblastoma cells (Y-79) to neurotrophins. - 2000 - Investigative ophthalmology & visual science - 41 P1932-9
Wagner N, Wagner KD, Sefton M, Rodrì­guez-Tébar A, and Grantyn,R

Combined treatment with ramipril and metoprolol prevents changes in the creatine kinase isoenzyme system and improves hemodynamic function in rat hearts after myocardial infarction. - 2000 - Cardiovascular drugs and therapy / sponsored by the International Society of Cardiovascular Pharmacotherapy - 14 P597-606
Theres HP, Wagner KD, Romberg D, Feig C, Strube S, Leiterer KP, Gì¼nther J, Stangl K, Baumann G, and Schimke,I

Tie2 receptor expression is stimulated by hypoxia and proinflammatory cytokines in human endothelial cells. - 2000 - Circulation research - 87 P370-7
Willam C, Koehne P, Jì¼rgensen JS, Grì¤fe M, Wagner KD, Bachmann S, Frei U, and Eckardt,KU

Myocardial contractility after infarction and carnitine palmitoyltransferase I inhibition in rats. - 2000 - European journal of pharmacology - 406 P123-6
Gì¼nther J, Wagner K, Theres H, Schimke I, Born A, Scholz H, and Vetter,R

Effects of metoprolol and ramipril on action potentials after myocardial infarction in rats. - 2000 - European journal of pharmacology - 388 P263-6
Wagner K, Kamkin A, Kiseleva I, Theres H, Scholz H, and Gì¼nther,J

Mechanically induced potentials in fibroblasts from human right atrium. - 1999 - Experimental physiology - 84 P347-56
Kamkin A, Kiseleva I, Wagner KD, Lammerich A, Bohm J, Persson PB, and Gì¼nther,J

Electrophysiological properties of mechanosensitive atrial fibroblasts from chronic infarcted rat heart. - 1998 - Journal of molecular and cellular cardiology - 30 P1083-93
Kiseleva I, Kamkin A, Pylaev A, Kondratjev D, Leiterer KP, Theres H, Wagner KD, Persson PB, and Gì¼nther,J

Decreased susceptibility of contractile function to hypoxia/reoxygenation in chronic infarcted rat hearts. - 1998 - Journal of molecular and cellular cardiology - 30 P2341-53
Wagner KD, Geil D, Schimke I, Stauss HM, Lammerich A, Theres H, Pfitzer G, Vetter R, and Gì¼nther,J

Contractile function of papillary muscle from rats with different infarct size after beta-adrenergic blockade and ACE-inhibition. - 1997 - Journal of molecular and cellular cardiology - 29 P2941-51
Wagner KD, Theres H, Born A, Strube S, Wunderlich N, Pfitzer G, Baumann G, and Gì¼nther,J

TRF2 acts as a transcriptional regulator in tumor angiogenesis. - Molecular & cellular oncology - 2 Pe988508
Maï ME, Wagner KD, Michiels JF, Gilson E, and Wagner,N

Effects of hypoxia, simulated ischemia and reoxygenation on the contractile function of human atrial trabeculae. - Molecular and cellular biochemistry - 160-161 P143-51
Lammerich A, Bohm J, Schimke I, Wagner KD, Storch E, and Gì¼nther,J

Cardiac fibroblasts and the mechano-electric feedback mechanism in healthy and diseased hearts. - Progress in biophysics and molecular biology - 82 P111-20
Kamkin A, Kiseleva I, Isenberg G, Wagner KD, Gì¼nther J, Theres H, and Scholz,H

 

 

 
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